[Ebooks] Biophysical Osteoblast Stimulation for Bone Grafting and Regeneration

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Biophysical Osteoblast Stimulation for Bone Grafting and Regeneration

Description:

This book integrates the current basic and clinical knowledge in the area of biophysical stimulation of osteoblast for in vitro and in vivo live bone generation. This innovative methodology and its applications are presented and discussed in several clinical conditions: treatment of fracture nonunion, spine stabilization, bone replacement after tumor resections, stabilization of failed joint endoprostheses in revision surgery and in treatment of bone loss (osteoporosis and osteopenia).

The author analyses different types of biophysical stimulation of osteoblasts for bone regeneration, e.g. mechanical (static and alternating, including distraction osteogenesis), electromagnetic (pulsed, alternating, static), light (at different spectrum range, including laser), acoustic (including ultrasound), RF etc. Moreover, he summarizes and discusses the most significant findings for in vitro bone generation and its resulting clinical use as autologous bone graft without surgical morbidity.

Reflecting the author’s extensive experience this book is an excellent source of knowledge and a valuable aid to clinical practice for all orthopedic surgeons, fellows, and researchers wanting to gain insights into this promising field.

Preface

Facts relating to attempted osseous transplantations are few, the details concerning them are meagre, and the deductions drawn from them have been received with dubiety.

Sir William Macewen. Observations concerning transplantation of bone. Illustrated by a case of inter-human osseous transplantation, whereby over twothirds of the shaft of a humerus was restored. Proceedings of the Royal Society of London 1981; 32:212–215.

This book, partially based on my Ph.D. thesis,1 provides an overview of the fascinating ability of bone to re-generate under external biophysical control. The clinical importance of this phenomenon is apparent because human skeletal support can recover after local or systemic damage. The main cellular component that governs this response is the osteoblast, which is highly susceptible to external biophysical stimulation.

This is not an encyclopedic text but rather an attempt to present the interrelation of cellular mechanisms with the potential to be tuned for the clinical application of different biophysical energies for bone regeneration by stimulating osteoblast metabolism.

Therefore, this text should help surgeons to understand the cellular mechanisms that underline the various currently used or predicted clinical methods for enhanced bone regeneration by biophysical methods.

Scientists may benefit from recognizing the clinical goals of the basic research into the biophysical stimulation of osteoblasts.

These mutual benefits are the primary goals of this book.

• Title: Biophysical Osteoblast Stimulation for Bone Grafting and Regeneration: From Basic Science to Clinical Applications
  
• Authors: Nahum Rosenberg
  
• Publisher: Springer
  
• Year: 2023
  
• Edition: – Edition
  
• Language: English
  
• Pages: 82
  
• Ebook: PDF
  
• File size: 5 MB
  
• ISBN Number:  3031069196, 9783031069192
  
• CBID: CBM392
  

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