Clinical Biochemistry and Metabolic Medicine 8e 2012
Were it not for the textbook Clinical Chemistry in Diagnosis and Treatment by Joan Zilva and Peter Pannall, I would not be a chemical pathologist. As a medical student, I was so struck by its clarity, depth and clinical relevance that I decided that theirs was the medical field I wished to work in.
Over the years, the fi eld of clinical biochemistry has changed radically. Confusingly, there is no consensus on the name for this fi eld of medicine, which is known variously as clinical chemistry, chemical pathology or clinical biochemistry, to name but a few. Additionally, the fi eld now overlaps with that of metabolic medicine, a clinical specialty involved with the management and treatment of patients with disorders of metabolism. Clinical biochemistry laboratories have become further automated, molecular biology technologies have entered the diagnostic arena, and chemical pathologists have become more clinically orientated towards running out-patient clinics for a variety of biochemical disturbances. This book aims to address these new changes. Indeed, it is diffi cult to imagine a branch of medicine that does not at some time require clinical biochemistry tests, which may not be too surprising, given the fact that every body cell is composed of chemicals!
Unfortunately, there have been some diffi culties in recent times, with a relative shortage of graduates entering the specialty, which has not been helped by some people’s attitude that clinical biochemistry is merely a laboratory factory churning out results that anyone can interpret. There are also concerns that medical student clinical biochemistry teaching may become ‘diluted’ as part of an expanding curriculum. It is hoped that this book will excite a new generation to enter this fascinating and essential fi eld, as well as benefi t patients as their doctors learn more about their biochemical and metabolic problems.
I am most grateful to Dr Sethsiri Wijeratne, Dr Alam Garrib (particularly for molecular biology expertise) and Dr Paul Eldridge for constructive criticism of the text. I am also grateful to Professor Philip Mayne for his earlier contributions and the anonymous medical student reviewer(s) who commented on the text. The book has also greatly benefi ted from the wise, helpful and experienced input of Dr Andrew Day – many thanks. Although every effort has been made to avoid inaccuracies and errors, it is almost inevitable that some may still be present, and feedback from readers is therefore welcome.
Martin Crook
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