Advances in Clinical Chemistry 2013 - Volume 61
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PREFACE
The third and final volume of the Advances in Clinical Chemistry series for 2013 is presented.
In Volume 61, a number of interesting and relevant topics in clinical laboratory diagnostics are presented. The first chapter provides a comprehensive review of the biochemistry of processed BNP molecular forms including their use in diagnosis and therapy of cardiovascular disease. The second chapter revisits the usefulness of troponins, specifically troponin T in myocardial damage and cardiovascular diseases. The following chapter focuses on markers associated with nonalcoholic steatohepatitis, the most common liver disease worldwide. The next chapter examines stateof-the-art laboratory tools to assess free and total thyroid hormones. Current methods of analysis are evaluated including the benefits of tandem mass spectrometry. The fifth chapter addresses the regenerating gene family. Through a variety of signaling pathways, Reg proteins play an important role in cell proliferation, migration, and apoptosis and may be relevant to a number of diseases including inflammation and cancer. The sixth and final chapter for this edition highlights the methods of analysis for circulating breast cancer cells and examines their potential role in primary diagnosis as well as disease recurrence and therapeutic response.
I thank each contributor of Volume 61 and my colleagues who contributed to peer review. I extend thanks to Sarah Lay and Helene Kabes for their expert editorial support at Elsevier.
I hope the final volume for 2013 will be enjoyed. Your comments are always appreciated.
I would like to dedicate Volume 61 to April 1, 1983. It is hard to believe that 30 years have passed.
The third and final volume of the Advances in Clinical Chemistry series for 2013 is presented.
In Volume 61, a number of interesting and relevant topics in clinical laboratory diagnostics are presented. The first chapter provides a comprehensive review of the biochemistry of processed BNP molecular forms including their use in diagnosis and therapy of cardiovascular disease. The second chapter revisits the usefulness of troponins, specifically troponin T in myocardial damage and cardiovascular diseases. The following chapter focuses on markers associated with nonalcoholic steatohepatitis, the most common liver disease worldwide. The next chapter examines stateof-the-art laboratory tools to assess free and total thyroid hormones. Current methods of analysis are evaluated including the benefits of tandem mass spectrometry. The fifth chapter addresses the regenerating gene family. Through a variety of signaling pathways, Reg proteins play an important role in cell proliferation, migration, and apoptosis and may be relevant to a number of diseases including inflammation and cancer. The sixth and final chapter for this edition highlights the methods of analysis for circulating breast cancer cells and examines their potential role in primary diagnosis as well as disease recurrence and therapeutic response.
I thank each contributor of Volume 61 and my colleagues who contributed to peer review. I extend thanks to Sarah Lay and Helene Kabes for their expert editorial support at Elsevier.
I hope the final volume for 2013 will be enjoyed. Your comments are always appreciated.
I would like to dedicate Volume 61 to April 1, 1983. It is hard to believe that 30 years have passed.
GREGORY S. MAKOWSKI
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