[Ebooks] Antiangiogenic Cancer Therapy

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In recent years, tremendous progress has been made in our understanding of molecula mechanisms and cellular regulation of angiogenesis in cancer. Despite this progress, clinical development of angiogenesis inhibitors for the treatment of cancer remains challenging. Given that solid tumors account for more than 85% of cancer mortality, and tumor growth and metastasis are dependent on blood vessels, targeting tumor angiogenesis is one of the most widely pursued therapeutic strategies today. Approaches to target angiogenesis in cancer include destroying the existing vasculature (antivascular) and inhibiting neovascularization (antiangiogenic). We hope that Antiangiogenic Cancer Therapy will stimulate the rapid translation and dissemination of basic science discoveries into novel clinical strategies that will provide more effective antiangiogenic therapies for cancer.

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