Amyloidosis - Mechanisms and Prospects for Therapy
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Amyloidoses are a heterogeneous group of diverse etiology diseases. They ar characterized by an endogenous production of abnormal proteins called amyloid proteins, which are not hydrosoluble, form depots in various organs and tissue of animals and humans and cause dysfunctions. Twenty-seven such proteins have been identified as amyloid precursors in humans. However, the answer why these roteins form aggregates and cause disease is not still completely clear. At present, there is not an effective treatment to prevent protein misfolding in these amyloid diseases.
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