Antimalarial Chemotherapy

We who are engrossed in the study of antimalarial chemotherapy are fond of repeating certain maxims. Malaria is one of the most important disease problems in the world. The control of malaria is increasingly limited by resistance to available drugs. New strategies for treating malaria are urgently needed. We should strive to identify new targets for antimalarial agents. Each of these maxims has reached the status of a cliché, but is nonetheless compelling. The complex biology of malaria parasites and extreme poverty in most malarious regions have locked us into an unrelenting continuation of endemic malaria in most of the tropical world. Meanwhile, drug resistance worsens, and it appears