Anticancer Therapeutics - S. Missailidis

There remains an urgent unmet clinical need to augment the efforts of surgeons and radiotherapists in combating localized malignant disease. Moreover, better strategies are required to deal with the all-too-common clinical scenario of patients presenting with disseminated metastatic disease, using systemic chemotherapy. In the 60-year history of cancer chemotherapy much has been achieved, particularly through the development of cytotoxic drugs in the 1950s and 1960s.