Analysis of Microarray Gene Expression Data

I thank Jeff Sklar and his former research team at the Brigham and Women’s Hospital for introducing me to microarray technology in 1999.

At that time, statistical methodology for analyzing microarray data was a new research field that needed much development and publishereports in the literature were sparse. It took me several weeks at Frank Kuo’s laboratory observing the procedures and details before I began to understand how gene expression is measured in microarray experiments.