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The Harriet Lane Handbook was frst developed in 1953 after Harrison Spencer (Chief Resident in 1950–1951) suggested that residents should
write a pocket-sized “pearl book.” As recounted by Henry Seidel, the frst editor of The Harriet Lane Handbook, “Six of us began without funds
and without [the] supervision of our elders, meeting sporadically around a table in the library of the Harriet Lane Home.
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